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Atomic Force Microscopy Studies Provide Direct Evidence for Dimerization of the HIV Restriction Factor APOBEC3G

APOBEC3G (A3G) is an antiviral protein that binds RNA and single-stranded DNA (ssDNA). The oligomerization state of A3G is likely to be influenced by these nucleic acid interactions. We applied the power of nanoimaging atomic force microscopy technology to characterize the role of ssDNA in A3G oligo...

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Detalles Bibliográficos
Autores principales:	Shlyakhtenko, Luda S., Lushnikov, Alexander Y., Li, Ming, Lackey, Lela, Harris, Reuben S., Lyubchenko, Yuri L.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030345/ https://www.ncbi.nlm.nih.gov/pubmed/21123176 http://dx.doi.org/10.1074/jbc.M110.195685

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