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Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD)
Microglial dysfunction is associated with the pathogenesis and progression of a number of neurodegenerative disorders including HIV associated dementia (HAD). HIV promotion of an M1 antigen presenting cell (APC) - like microglial phenotype, through the promotion of CD40 activity, may impair endogeno...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030526/ https://www.ncbi.nlm.nih.gov/pubmed/21223591 http://dx.doi.org/10.1186/1750-1326-6-3 |