Sildenafil Reduces Insulin-Resistance in Human Endothelial Cells

BACKGROUND: The efficacy of Phosphodiesterase 5 (PDE5) inhibitors to re-establish endothelial function is reduced in diabetic patients. Recent evidences suggest that therapy with PDE5 inhibitors, i.e. sildenafil, may increase the expression of nitric oxide synthase (NOS) proteins in the heart and ca...

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Detalles Bibliográficos
Autores principales: Mammi, Caterina, Pastore, Donatella, Lombardo, Marco F., Ferrelli, Francesca, Caprio, Massimiliano, Consoli, Claudia, Tesauro, Manfredi, Gatta, Lucia, Fini, Massimo, Federici, Massimo, Sbraccia, Paolo, Donadel, Giulia, Bellia, Alfonso, Rosano, Giuseppe M., Fabbri, Andrea, Lauro, Davide
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030559/
https://www.ncbi.nlm.nih.gov/pubmed/21297971
http://dx.doi.org/10.1371/journal.pone.0014542

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