Large Scale Loss of Data in Low-Diversity Illumina Sequencing Libraries Can Be Recovered by Deferred Cluster Calling

Massively parallel DNA sequencing is capable of sequencing tens of millions of DNA fragments at the same time. However, sequence bias in the initial cycles, which are used to determine the coordinates of individual clusters, causes a loss of fidelity in cluster identification on Illumina Genome Anal...

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Detalles Bibliográficos
Autores principales: Krueger, Felix, Andrews, Simon R., Osborne, Cameron S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030592/
https://www.ncbi.nlm.nih.gov/pubmed/21305042
http://dx.doi.org/10.1371/journal.pone.0016607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030592/
https://www.ncbi.nlm.nih.gov/pubmed/21305042
http://dx.doi.org/10.1371/journal.pone.0016607

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