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Characterizing Ligand-Gated Ion Channel Receptors with Genetically Encoded Ca(++) Sensors

We present a cell based system and experimental approach to characterize agonist and antagonist selectivity for ligand-gated ion channels (LGIC) by developing sensor cells stably expressing a Ca(2+) permeable LGIC and a genetically encoded Förster (or fluorescence) resonance energy transfer (FRET)-b...

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Detalles Bibliográficos
Autores principales:	Yamauchi, John G., Nemecz, Ákos, Nguyen, Quoc Thang, Muller, Arnaud, Schroeder, Lee F., Talley, Todd T., Lindstrom, Jon, Kleinfeld, David, Taylor, Palmer
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030600/ https://www.ncbi.nlm.nih.gov/pubmed/21305050 http://dx.doi.org/10.1371/journal.pone.0016519

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