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Contribution of a Common Variant in the Promoter of the 1-α-Hydroxylase Gene (CYP27B1) to Fracture Risk in the Elderly

CYP27B1 encodes mitochondrial 1α-hydroxylase, which converts 25-hydroxyvitamin D to its active 1,25-dihydroxylated metabolite. We tested the hypothesis that common variants in the CYP27B1 promoter are associated with fracture risk. The study was designed as a population-based genetic association stu...

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Detalles Bibliográficos
Autores principales:	Clifton-Bligh, Roderick J., Nguyen, Tuan V., Au, Amy, Bullock, Martyn, Cameron, Ian, Cumming, Robert, Chen, Jian Sheng, March, Lyn M., Seibel, Markus J., Sambrook, Philip N.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030947/ https://www.ncbi.nlm.nih.gov/pubmed/21107545 http://dx.doi.org/10.1007/s00223-010-9434-4

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