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Pott's disease in children

BACKGROUND: The incidence of tuberculosis is increasing, and skeletal tuberculosis accounts for 10-20% of all extrapulmonary cases. Spinal tuberculosis occurs mostly in children and young adults. It causes bone destruction, spinal deformity and neural complications. MATERIALS AND METHODS: Our study...

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Autores principales: Benzagmout, Mohammed, Boujraf, Saïd, Chakour, Khalid, Chaoui, Mohammed El Faïz
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031051/
https://www.ncbi.nlm.nih.gov/pubmed/21297923
http://dx.doi.org/10.4103/2152-7806.75459
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author Benzagmout, Mohammed
Boujraf, Saïd
Chakour, Khalid
Chaoui, Mohammed El Faïz
author_facet Benzagmout, Mohammed
Boujraf, Saïd
Chakour, Khalid
Chaoui, Mohammed El Faïz
author_sort Benzagmout, Mohammed
collection PubMed
description BACKGROUND: The incidence of tuberculosis is increasing, and skeletal tuberculosis accounts for 10-20% of all extrapulmonary cases. Spinal tuberculosis occurs mostly in children and young adults. It causes bone destruction, spinal deformity and neural complications. MATERIALS AND METHODS: Our study includes 37 children (below 15 years of age) with spinal tuberculosis treated in our department in the last 6 years. The demographic data, clinical profile, surgical intervention and outcome of these children are reported. RESULTS: The mean age ranged from 4 to 15 years, with an average of 9.1 years, and the male/female ratio was 1.8. Thirty patients (81%) had progressive inflammatory rachialgia and only six patients (16.2%) had neurological symptoms. The lumbar spine was mostly affected (23 cases). All patients have benefited from antituberculous chemotherapy (Regimen 2SRHZ/10RH) associated with spinal immobilization during 3 months. The surgical treatment was indicated in seven patients because of the presence of large bilateral abscess of the psoas muscle in one patient and the presence of severe neurological symptoms in the six remaining patients. The evolution was favorable in all cases, including those with neurological symptoms. There was no case of death and the length of follow-up for these patients ranged between 1 and 4 years. CONCLUSION: Spinal tuberculosis is still a prevalent disease in developing countries, mainly occurring in children. Complications of the disease can be devastating because of its ability to cause bone destruction, spinal deformity and paraplegia. Therefore, an early diagnosis and establishment of treatment are necessary to expect a good outcome.
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spelling pubmed-30310512011-02-04 Pott's disease in children Benzagmout, Mohammed Boujraf, Saïd Chakour, Khalid Chaoui, Mohammed El Faïz Surg Neurol Int Original Article BACKGROUND: The incidence of tuberculosis is increasing, and skeletal tuberculosis accounts for 10-20% of all extrapulmonary cases. Spinal tuberculosis occurs mostly in children and young adults. It causes bone destruction, spinal deformity and neural complications. MATERIALS AND METHODS: Our study includes 37 children (below 15 years of age) with spinal tuberculosis treated in our department in the last 6 years. The demographic data, clinical profile, surgical intervention and outcome of these children are reported. RESULTS: The mean age ranged from 4 to 15 years, with an average of 9.1 years, and the male/female ratio was 1.8. Thirty patients (81%) had progressive inflammatory rachialgia and only six patients (16.2%) had neurological symptoms. The lumbar spine was mostly affected (23 cases). All patients have benefited from antituberculous chemotherapy (Regimen 2SRHZ/10RH) associated with spinal immobilization during 3 months. The surgical treatment was indicated in seven patients because of the presence of large bilateral abscess of the psoas muscle in one patient and the presence of severe neurological symptoms in the six remaining patients. The evolution was favorable in all cases, including those with neurological symptoms. There was no case of death and the length of follow-up for these patients ranged between 1 and 4 years. CONCLUSION: Spinal tuberculosis is still a prevalent disease in developing countries, mainly occurring in children. Complications of the disease can be devastating because of its ability to cause bone destruction, spinal deformity and paraplegia. Therefore, an early diagnosis and establishment of treatment are necessary to expect a good outcome. Medknow Publications & Media Pvt Ltd 2011-01-11 /pmc/articles/PMC3031051/ /pubmed/21297923 http://dx.doi.org/10.4103/2152-7806.75459 Text en Copyright: © 2011 Benzagmout M http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
spellingShingle Original Article
Benzagmout, Mohammed
Boujraf, Saïd
Chakour, Khalid
Chaoui, Mohammed El Faïz
Pott's disease in children
title Pott's disease in children
title_full Pott's disease in children
title_fullStr Pott's disease in children
title_full_unstemmed Pott's disease in children
title_short Pott's disease in children
title_sort pott's disease in children
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031051/
https://www.ncbi.nlm.nih.gov/pubmed/21297923
http://dx.doi.org/10.4103/2152-7806.75459
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