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Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide

BACKGROUND: "Nubiotics" are synthetic oligonucleotides and nucleotides with nuclease-resistant backbones, and are fully protonated for enhanced ability to be taken up by bacterial cells. Nu-3 [butyl-phosphate-5'-thymidine-3'-phosphate-butyl], one of the family members of Nubiotic...

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Detalles Bibliográficos
Autores principales:	Cao, Shanping, Sun, Lun-Quan, Wang, Ming
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031213/ https://www.ncbi.nlm.nih.gov/pubmed/21232163 http://dx.doi.org/10.1186/1476-0711-10-1

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