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Phosphorylation of threonine 154 in p40(phox) is an important physiological signal for activation of the neutrophil NADPH oxidase
The neutrophil nicotinamide adenine dinucleotide phosphate-oxidase is a multisubunit enzyme (comprising gp91(phox), p22(phox), p67(phox), p40(phox), p47(phox), and Rac) that plays a vital role in microbial killing. The recent discovery of a chronic granulomatous disease patient who expresses a mutan...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031388/ https://www.ncbi.nlm.nih.gov/pubmed/20861461 http://dx.doi.org/10.1182/blood-2010-08-300889 |