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Phosphorylation of threonine 154 in p40(phox) is an important physiological signal for activation of the neutrophil NADPH oxidase

The neutrophil nicotinamide adenine dinucleotide phosphate-oxidase is a multisubunit enzyme (comprising gp91(phox), p22(phox), p67(phox), p40(phox), p47(phox), and Rac) that plays a vital role in microbial killing. The recent discovery of a chronic granulomatous disease patient who expresses a mutan...

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Detalles Bibliográficos
Autores principales:	Chessa, Tamara A. M., Anderson, Karen E., Hu, Yanhua, Xu, Qingbo, Rausch, Oliver, Stephens, Len R., Hawkins, Phillip T.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2010
Materias:	Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031388/ https://www.ncbi.nlm.nih.gov/pubmed/20861461 http://dx.doi.org/10.1182/blood-2010-08-300889

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