Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by Bilirubin at the Blood-CSF and Blood-Brain Barriers in the Gunn Rat

Accumulation of unconjugated bilirubin (UCB) in the brain causes bilirubin encephalopathy. Pgp (ABCb1) and Mrp1 (ABCc1), highly expressed in the blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB) respectively, may modulate the accumulation of UCB in brain. We examined the effect...

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Detalles Bibliográficos
Autores principales: Gazzin, Silvia, Berengeno, Andrea Lorena, Strazielle, Nathalie, Fazzari, Francesco, Raseni, Alan, Ostrow, J. Donald, Wennberg, Richard, Ghersi-Egea, Jean-François, Tiribelli, Claudio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031532/
https://www.ncbi.nlm.nih.gov/pubmed/21297965
http://dx.doi.org/10.1371/journal.pone.0016165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031532/
https://www.ncbi.nlm.nih.gov/pubmed/21297965
http://dx.doi.org/10.1371/journal.pone.0016165

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