Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

Statins inhibit the proximal steps of cholesterol biosynthesis, and are linked to health benefits in various conditions, including cancer and lung disease. We have previously investigated apoptotic pathways triggered by statins in airway mesenchymal cells, and identified reduced prenylation of small...

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Detalles Bibliográficos
Autores principales: Ghavami, Saeid, Mutawe, Mark M., Sharma, Pawan, Yeganeh, Behzad, McNeill, Karol D., Klonisch, Thomas, Unruh, Helmut, Kashani, Hessam H., Schaafsma, Dedmer, Los, Marek, Halayko, Andrew J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031577/
https://www.ncbi.nlm.nih.gov/pubmed/21304979
http://dx.doi.org/10.1371/journal.pone.0016523

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