Activation of the Canonical Wnt/β-Catenin Pathway in ATF3-Induced Mammary Tumors

Female transgenic mice that constitutively overexpress the transcription factor ATF3 in the basal epithelium of the mammary gland develop mammary carcinomas with high frequency, but only if allowed to mate and raise pups early in life. This transgenic mouse model system reproduces some features of h...

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Detalles Bibliográficos
Autores principales: Yan, Leqin, Coletta, Luis Della, Powell, K. Leslie, Shen, Jianjun, Thames, Howard, Aldaz, C. Marcelo, MacLeod, Michael C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031586/
https://www.ncbi.nlm.nih.gov/pubmed/21304988
http://dx.doi.org/10.1371/journal.pone.0016515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031586/
https://www.ncbi.nlm.nih.gov/pubmed/21304988
http://dx.doi.org/10.1371/journal.pone.0016515

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