Cytosolic Guanine Nucledotide Binding Deficient Form of Transglutaminase 2 (R580a) Potentiates Cell Death in Oxygen Glucose Deprivation

Transglutaminase 2 (TG2) is a hypoxia-responsive protein that is a calcium-activated transamidating enzyme, a GTPase and a scaffolding/linker protein. Upon activation TG2 undergoes a large conformational change, which likely affects not only its enzymatic activities but its non-catalytic functions a...

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Detalles Bibliográficos
Autores principales: Colak, Gozde, Keillor, Jeffrey W., Johnson, Gail V. W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031627/
https://www.ncbi.nlm.nih.gov/pubmed/21304968
http://dx.doi.org/10.1371/journal.pone.0016665

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