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Functional Promoter Polymorphisms Govern Differential Expression of HMG-CoA Reductase Gene in Mouse Models of Essential Hypertension

3-Hydroxy-3-methylglutaryl-coenzyme A [HMG-CoA] reductase gene (Hmgcr) is a susceptibility gene for essential hypertension. Sequencing of the Hmgcr locus in genetically hypertensive BPH (blood pressure high), genetically hypotensive BPL (blood pressure low) and genetically normotensive BPN (blood pr...

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Detalles Bibliográficos
Autores principales: Sonawane, Parshuram J., Sahu, Bhavani S., Sasi, Binu K., Geedi, Parimala, Lenka, Govinda, Mahapatra, Nitish R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031630/
https://www.ncbi.nlm.nih.gov/pubmed/21304971
http://dx.doi.org/10.1371/journal.pone.0016661