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Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours

BACKGROUND: The eicosanoid signalling pathway promotes the progression of malignancies through the production of proliferative prostaglandins (PGs). Cytosolic phospholipase A(2)α (cPLA(2)α) activity provides the substrate for cyclooxygenase-dependent PG release, and we have previously found that cPL...

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Detalles Bibliográficos
Autores principales:	Caiazza, F, McCarthy, N S, Young, L, Hill, A D K, Harvey, B J, Thomas, W
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031888/ https://www.ncbi.nlm.nih.gov/pubmed/21119660 http://dx.doi.org/10.1038/sj.bjc.6606025

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