Cargando…

Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis

A 14-year-old girl presenting with visual loss in both eyes was diagnosed to have healed toxoplasma retinochoroiditis in the right eye with active choroidal neovascularization (CNV) secondary to toxoplasmosis in the left. She underwent combination photodynamic therapy (PDT) and intravitreal bevacizu...

Descripción completa

Detalles Bibliográficos
Autores principales: Rishi, Pukhraj, Venkataraman, Anusha, Rishi, Ekta
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032250/
https://www.ncbi.nlm.nih.gov/pubmed/21157079
http://dx.doi.org/10.4103/0301-4738.73728
_version_ 1782197436857450496
author Rishi, Pukhraj
Venkataraman, Anusha
Rishi, Ekta
author_facet Rishi, Pukhraj
Venkataraman, Anusha
Rishi, Ekta
author_sort Rishi, Pukhraj
collection PubMed
description A 14-year-old girl presenting with visual loss in both eyes was diagnosed to have healed toxoplasma retinochoroiditis in the right eye with active choroidal neovascularization (CNV) secondary to toxoplasmosis in the left. She underwent combination photodynamic therapy (PDT) and intravitreal bevacizumab as primary treatment. PDT was performed as per the ‘Treatment of Age-related Macular Degeneration by Photodynamic therapy’ study protocol and was followed by intravitreal bevacizumab after 2 days. CNV regressed at 8 weeks of follow-up and remained stable at 8 months of follow-up. The initial visual acuity improved from 20/120 to 20/30. Combination therapy with PDT and intravitreal bevacizumab appears to be effective in the treatment of CNV secondary to toxoplasma retinochoroiditis.
format Text
id pubmed-3032250
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Medknow Publications
record_format MEDLINE/PubMed
spelling pubmed-30322502011-02-09 Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis Rishi, Pukhraj Venkataraman, Anusha Rishi, Ekta Indian J Ophthalmol Brief Communications A 14-year-old girl presenting with visual loss in both eyes was diagnosed to have healed toxoplasma retinochoroiditis in the right eye with active choroidal neovascularization (CNV) secondary to toxoplasmosis in the left. She underwent combination photodynamic therapy (PDT) and intravitreal bevacizumab as primary treatment. PDT was performed as per the ‘Treatment of Age-related Macular Degeneration by Photodynamic therapy’ study protocol and was followed by intravitreal bevacizumab after 2 days. CNV regressed at 8 weeks of follow-up and remained stable at 8 months of follow-up. The initial visual acuity improved from 20/120 to 20/30. Combination therapy with PDT and intravitreal bevacizumab appears to be effective in the treatment of CNV secondary to toxoplasma retinochoroiditis. Medknow Publications 2011 /pmc/articles/PMC3032250/ /pubmed/21157079 http://dx.doi.org/10.4103/0301-4738.73728 Text en © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communications
Rishi, Pukhraj
Venkataraman, Anusha
Rishi, Ekta
Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis
title Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis
title_full Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis
title_fullStr Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis
title_full_unstemmed Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis
title_short Combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis
title_sort combination photodynamic therapy and bevacizumab for choroidal neovascularization associated with toxoplasmosis
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032250/
https://www.ncbi.nlm.nih.gov/pubmed/21157079
http://dx.doi.org/10.4103/0301-4738.73728
work_keys_str_mv AT rishipukhraj combinationphotodynamictherapyandbevacizumabforchoroidalneovascularizationassociatedwithtoxoplasmosis
AT venkataramananusha combinationphotodynamictherapyandbevacizumabforchoroidalneovascularizationassociatedwithtoxoplasmosis
AT rishiekta combinationphotodynamictherapyandbevacizumabforchoroidalneovascularizationassociatedwithtoxoplasmosis