Giant unilamellar vesicles (GUVs) as a new tool for analysis of caspase-8/Bid-FL complex binding to cardiolipin and its functional activity

Cardiolipin (CL) has recently been shown to be both an anchor and an essential activating platform for caspase-8 on mitochondria. These platforms may be at the mitochondrial contact sites in which truncated Bid (tBid) has been demonstrated to be located. A possible role for CL is to anchor caspase-8...

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Detalles Bibliográficos
Autores principales: Jalmar, O, García-Sáez, A J, Berland, L, Gonzalvez, F, Petit, P X
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032292/
https://www.ncbi.nlm.nih.gov/pubmed/21368876
http://dx.doi.org/10.1038/cddis.2010.81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032292/
https://www.ncbi.nlm.nih.gov/pubmed/21368876
http://dx.doi.org/10.1038/cddis.2010.81

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