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p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53

The question of how neural progenitor cells maintain its self-renewal throughout life is a fundamental problem in cell biology with implications in cancer, aging and neurodegenerative diseases. In this work, we have analyzed the p73 function in embryonic neural progenitor cell biology using the neur...

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Detalles Bibliográficos
Autores principales: Gonzalez-Cano, L, Herreros-Villanueva, M, Fernandez-Alonso, R, Ayuso-Sacido, A, Meyer, G, Garcia-Verdugo, J M, Silva, A, Marques, M M, Marin, M C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032295/
https://www.ncbi.nlm.nih.gov/pubmed/21368881
http://dx.doi.org/10.1038/cddis.2010.87