c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle aging

This study shows that forcing c-Flip overexpression in undifferentiated skeletal myogenic cells in vivo results in early aging muscle phenotype. In the transgenic mice, adult muscle histology, histochemistry and biochemistry show strong alterations: reduction of fibers size and muscle mass, mitochon...

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Detalles Bibliográficos
Autores principales: Giampietri, C, Petrungaro, S, Coluccia, P, Antonangeli, F, Giannakakis, K, Faraggiana, T, Filippini, A, Cossu, G, Ziparo, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032302/
https://www.ncbi.nlm.nih.gov/pubmed/21364645
http://dx.doi.org/10.1038/cddis.2010.17

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