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A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts
Mouse embryonic fibroblasts (MEFs) are commonly grown in cell culture and are known to enter senescence after a low number of passages as a result of oxidative stress. Oxidative stress has also been suggested to promote centrosome disruption; however, the contribution of this organelle to senescence...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032305/ https://www.ncbi.nlm.nih.gov/pubmed/21364642 http://dx.doi.org/10.1038/cddis.2010.12 |