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JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis
Yes-associated protein (YAP) regulates DNA damage and chemosensitivity, as well as functioning as a pro-growth, cell size regulator. For both of its roles, regulation by phosphorylation is crucial. We undertook an in vitro screen to identify novel YAP kinases to discover new signaling pathways to be...
Autores principales: | Tomlinson, V, Gudmundsdottir, K, Luong, P, Leung, K-Y, Knebel, A, Basu, S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032333/ https://www.ncbi.nlm.nih.gov/pubmed/21364637 http://dx.doi.org/10.1038/cddis.2010.7 |
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