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Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death
Galectin-1 (gal-1), an endogenous β-galactoside-binding protein, triggers T-cell death through several mechanisms including the death receptor and the mitochondrial apoptotic pathway. In this study we first show that gal-1 initiates the activation of c-Jun N-terminal kinase (JNK), mitogen-activated...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032336/ https://www.ncbi.nlm.nih.gov/pubmed/21364631 http://dx.doi.org/10.1038/cddis.2010.1 |