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Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells

Pro-survival signalling mediated by the androgen receptor (AR) is implicated as a key contributor to prostate carcinogenesis. As prostate tumours are characterized by nutrient-poor, hypoxic and acidified microenvironments, one mechanism whereby AR signalling may contribute to survival is by promotin...

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Detalles Bibliográficos
Autores principales:	Bennett, H L, Fleming, J T, O'Prey, J, Ryan, K M, Leung, H Y
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032338/ https://www.ncbi.nlm.nih.gov/pubmed/21364676 http://dx.doi.org/10.1038/cddis.2010.50

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