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Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease

The formation of cerebral senile plaques composed of amyloid β peptide (Aβ) is a fundamental feature of Alzheimer's disease (AD). Glial cells and more specifically microglia become reactive in the presence of Aβ. In a triple transgenic model of AD (3 × Tg-AD), we found a significant increase in...

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Detalles Bibliográficos
Autores principales:	Rodríguez, J J, Witton, J, Olabarria, M, Noristani, H N, Verkhratsky, A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032511/ https://www.ncbi.nlm.nih.gov/pubmed/21364611 http://dx.doi.org/10.1038/cddis.2009.2

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