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Drosophila happyhour modulates JNK-dependent apoptosis

Mitogen-activated protein kinase kinase kinase kinase-3 (MAP4K3) is a Ste20 kinase family member that modulates multiple signal transduction pathways. We recently identified MAP4K3 as proapoptotic kinase using an RNA interference screening approach. In mammalian cells, MAP4K3 enhances the mitochondr...

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Detalles Bibliográficos
Autores principales:	Lam, D, Shah, S, de Castro, I P, Loh, S H Y, Martins, L M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032524/ https://www.ncbi.nlm.nih.gov/pubmed/21364671 http://dx.doi.org/10.1038/cddis.2010.44

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