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Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy
Evidence is mounting that proinflammatory and proapoptotic thioredoxin-interacting protein (TXNIP) has a causative role in the development of diabetes. However, there are no studies investigating the role of TXNIP in diabetic retinopathy (DR). Here, we show that, in diabetic rats, TXNIP expression a...
Autores principales: | Perrone, L, Devi, T S, Hosoya, K-I, Terasaki, T, Singh, L P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032527/ https://www.ncbi.nlm.nih.gov/pubmed/21364670 http://dx.doi.org/10.1038/cddis.2010.42 |
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