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Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis
The bacterial second messenger bis-(3′–5′) cyclic dimeric guanosine monophosphate (c-di-GMP) has emerged as a central regulator for biofilm formation. Increased cellular c-di-GMP levels lead to stable cell attachment, which in Pseudomonas fluorescens requires the transmembrane receptor LapD. LapD ex...
Autores principales: | Navarro, Marcos V. A. S., Newell, Peter D., Krasteva, Petya V., Chatterjee, Debashree, Madden, Dean R., O'Toole, George A., Sondermann, Holger |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032553/ https://www.ncbi.nlm.nih.gov/pubmed/21304926 http://dx.doi.org/10.1371/journal.pbio.1000588 |
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