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KCNE1 D85N polymorphism — a sex-specific modifier in type 1 long QT syndrome?

BACKGROUND: Long QT syndrome (LQTS) is an inherited ion channel disorder manifesting with prolongation of the cardiac repolarization phase and severe ventricular arrhythmias. The common KCNE1 D85N potassium channel variant prolongs QT interval by inhibiting I(Ks )(KCNQ1) and I(Kr )(KCNH2) currents a...

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Detalles Bibliográficos
Autores principales:	Lahtinen, Annukka M, Marjamaa, Annukka, Swan, Heikki, Kontula, Kimmo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032654/ https://www.ncbi.nlm.nih.gov/pubmed/21244686 http://dx.doi.org/10.1186/1471-2350-12-11

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