Cargando…
Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent
BACKGROUND: Despite an ever-improving understanding of the molecular biology of cancer, the treatment of most cancers has not changed dramatically in the past three decades and drugs that do not discriminate between tumor cells and normal tissues remain the mainstays of anticancer therapy. Since Hsp...
Autores principales: | Horibe, Tomohisa, Kohno, Masayuki, Haramoto, Mari, Ohara, Koji, Kawakami, Koji |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032679/ https://www.ncbi.nlm.nih.gov/pubmed/21235734 http://dx.doi.org/10.1186/1479-5876-9-8 |
Ejemplares similares
-
Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells
por: Horibe, Tomohisa, et al.
Publicado: (2012) -
Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide
por: Horibe, Tomohisa, et al.
Publicado: (2014) -
A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells
por: Kawamoto, Megumi, et al.
Publicado: (2011) -
Targeting Interleukin-4 Receptor Alpha by Hybrid Peptide for Novel Biliary Tract Cancer Therapy
por: Seto, Kahori, et al.
Publicado: (2014) -
Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma
por: Kikuchi, Osamu, et al.
Publicado: (2016)