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Global gene expression profile progression in Gaucher disease mouse models

BACKGROUND: Gaucher disease is caused by defective glucocerebrosidase activity and the consequent accumulation of glucosylceramide. The pathogenic pathways resulting from lipid laden macrophages (Gaucher cells) in visceral organs and their abnormal functions are obscure. RESULTS: To elucidate this p...

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Detalles Bibliográficos
Autores principales:	Xu, You-Hai, Jia, Li, Quinn, Brian, Zamzow, Matthew, Stringer, Keith, Aronow, Bruce, Sun, Ying, Zhang, Wujuan, Setchell, Kenneth DR, Grabowski, Gregory A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032697/ https://www.ncbi.nlm.nih.gov/pubmed/21223590 http://dx.doi.org/10.1186/1471-2164-12-20

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