Cargando…

Potency, Efficacy and Durability of DNA/DNA, DNA/Protein and Protein/Protein Based Vaccination Using gp63 Against Leishmania donovani in BALB/c Mice

BACKGROUND: Visceral leishmaniasis (VL) caused by an intracellular protozoan parasite Leishmania, is fatal in the absence of treatment. At present there are no effective vaccines against any form of leishmaniasis. Here, we evaluate the potency, efficacy and durability of DNA/DNA, DNA-prime/Protein-b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mazumder, Saumyabrata, Maji, Mithun, Das, Amrita, Ali, Nahid
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032732/ https://www.ncbi.nlm.nih.gov/pubmed/21311597 http://dx.doi.org/10.1371/journal.pone.0014644

Ejemplares similares

Potentiating Effects of MPL on DSPC Bearing Cationic Liposomes Promote Recombinant GP63 Vaccine Efficacy: High Immunogenicity and Protection
por: Mazumder, Saumyabrata, et al.
Publicado: (2011)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Insights from the analysis of a predicted model of gp63 in Leishmania donovani
por: Razzazan, Ali, et al.
Publicado: (2008)

Leishmania mexicana Gp63 cDNA Using Gene Gun Induced Higher Immunity to L. mexicana Infection Compared to Soluble Leishmania Antigen in BALB/C
por: Rezvan, H, et al.
Publicado: (2011)

Absence of Metalloprotease GP63 Alters the Protein Content of Leishmania Exosomes
por: Hassani, Kasra, et al.
Publicado: (2014)

HO-3867 Induces ROS-Dependent Stress Response and Apoptotic Cell Death in Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2021)

Differential Immune Response against Recombinant Leishmania donovani Peroxidoxin 1 and Peroxidoxin 2 Proteins in BALB/c Mice
por: Daifalla, Nada S., et al.
Publicado: (2015)

The Absence of C-5 DNA Methylation in Leishmania donovani Allows DNA Enrichment from Complex Samples
por: Cuypers, Bart, et al.
Publicado: (2020)

RNA-Seq Revealed Expression of Many Novel Genes Associated With Leishmania donovani Persistence and Clearance in the Host Macrophage
por: Shadab, Mohammad, et al.
Publicado: (2019)

Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani : Evidence for Antigen Synergy and Protection
por: Das, Amrita, et al.
Publicado: (2014)

Modulation of Splenic B Cell Subsets during Experimental Leishmania donovani Infection in BALB/c Mice
por: Mondal, Koushik, et al.
Publicado: (2021)

Identification of internalin-A-like virulent proteins in Leishmania donovani
por: Mukherjee, Ishita, et al.
Publicado: (2016)

Therapy with Sodium Stibogluconate in Stearylamine-Bearing Liposomes Confers Cure against SSG-Resistant Leishmania donovani in BALB/c Mice
por: Roychoudhury, Jayeeta, et al.
Publicado: (2011)

Oxidative Stress-Mediated Overexpression of Uracil DNA Glycosylase in Leishmania donovani Confers Tolerance against Antileishmanial Drugs
por: Mishra, Anshul, et al.
Publicado: (2018)

Correction: Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani: Evidence for Antigen Synergy and Protection
por: Das, Amrita, et al.
Publicado: (2015)

Impact of Leishmania metalloprotease GP63 on macrophage signaling
por: Isnard, Amandine, et al.
Publicado: (2012)

Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages
por: Marr, Alexandra K., et al.
Publicado: (2014)

The immunogenicity and protective immunity of multi-epitopes DNA prime-protein boost vaccines encoding Amastin-Kmp-11, Kmp11-Gp63 and Amastin-Gp63 against visceral leishmaniasis
por: Zhang, Jianhui, et al.
Publicado: (2020)

Tissue/Biofluid Specific Molecular Cartography of Leishmania donovani Infected BALB/c Mice: Deciphering Systemic Reprogramming
por: Das, Sanchita, et al.
Publicado: (2021)

Characterization of the DNA-binding domain and identification of the active site residue in the ‘Gyr A’ half of Leishmania donovani topoisomerase II
por: Sengupta, Tanushri, et al.
Publicado: (2005)

A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells
por: Maji, Mithun, et al.
Publicado: (2016)

Bioflavonoid-Induced Apoptosis and DNA Damage in Amastigotes and Promastigotes of Leishmania donovani: Deciphering the Mode of Action
por: Mehwish, Shaila, et al.
Publicado: (2021)

Retraction of ‘Functional dissection of the C‐terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani’
por: Sengupta, Tanushri, et al.
Publicado: (2021)

The role of Leishmania GP63 in the modulation of innate inflammatory response to Leishmania major infection
por: Chan, Aretha, et al.
Publicado: (2021)

Genome Plasticity in Cultured Leishmania donovani: Comparison of Early and Late Passages
por: Sinha, Roma, et al.
Publicado: (2018)

Coadministration of the Three Antigenic Leishmania infantum Poly (A) Binding Proteins as a DNA Vaccine Induces Protection against Leishmania major Infection in BALB/c Mice
por: Soto, Manuel, et al.
Publicado: (2015)

Comprehensive Identification of mRNA-Binding Proteins of Leishmania donovani by Interactome Capture
por: Nandan, Devki, et al.
Publicado: (2017)

An insight into differential protein abundance throughout Leishmania donovani promastigote growth and differentiation
por: Alcolea, Pedro J., et al.
Publicado: (2022)

Evasion of Host Defence by Leishmania donovani: Subversion of Signaling Pathways
por: Shadab, Md., et al.
Publicado: (2011)

Deletion Study of DNA Topoisomerase IB from Leishmania donovani: Searching for a Minimal Functional Heterodimer
por: Díaz González, Rosario, et al.
Publicado: (2007)

Leishmania donovani induced Unfolded Protein Response delays host cell apoptosis in PERK dependent manner
por: Abhishek, Kumar, et al.
Publicado: (2018)

Xenodiagnosis of Leishmania donovani in BALB/c mice using Phlebotomus orientalis: a new laboratory model
por: Sadlova, Jovana, et al.
Publicado: (2015)

Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b
por: Singh, Ruby, et al.
Publicado: (2016)

Leishmania donovani Infection Enhances Lateral Mobility of Macrophage Membrane Protein Which Is Reversed by Liposomal Cholesterol
por: Ghosh, Moumita, et al.
Publicado: (2014)

On Transient Infections with Leishmania Donovani in Man and Animals
por: Knowles, R., et al.
Publicado: (1924)

Over-Expression of Cysteine Leucine Rich Protein Is Related to SAG Resistance in Clinical Isolates of Leishmania donovani
por: Das, Sanchita, et al.
Publicado: (2015)

DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival
por: Yadav, Aarti, et al.
Publicado: (2020)

Mitochondrial Associated Ubiquitin Fold Modifier-1 Mediated Protein Conjugation in Leishmania donovani
por: Gannavaram, Sreenivas, et al.
Publicado: (2011)

A small heat shock protein is essential for thermotolerance and intracellular survival of Leishmania donovani
por: Hombach, Antje, et al.
Publicado: (2014)

Characterization of a Novel Putative S-Adenosylmethionine Decarboxylase-Like Protein from Leishmania donovani
por: Singh, Saurabh Pratap, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_oj7q5c4ae5dbfcnq02acaacr7a