Overexpression of BMI-1 Promotes Cell Growth and Resistance to Cisplatin Treatment in Osteosarcoma

BACKGROUND: BMI-1 is a member of the polycomb group of genes (PcGs), and it has been implicated in the development and progression of several malignancies, but its role in osteosarcoma remains to be elucidated. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we found that BMI-1 was overexpress...

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Detalles Bibliográficos
Autores principales: Wu, Zhihong, Min, Li, Chen, Dafu, Hao, Dongsheng, Duan, Yuanhui, Qiu, Guixing, Wang, Yipeng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032734/
https://www.ncbi.nlm.nih.gov/pubmed/21311599
http://dx.doi.org/10.1371/journal.pone.0014648

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