Histone Deacetylase Activity Modulates Alternative Splicing

There is increasing evidence to suggest that splicing decisions are largely made when the nascent RNA is still associated with chromatin. Here we demonstrate that activity of histone deacetylases (HDACs) influences splice site selection. Using splicing-sensitive microarrays, we identified ∼700 genes...

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Detalles Bibliográficos
Autores principales: Hnilicová, Jarmila, Hozeifi, Samira, Dušková, Eva, Icha, Jaroslav, Tománková, Tereza, Staněk, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032741/
https://www.ncbi.nlm.nih.gov/pubmed/21311748
http://dx.doi.org/10.1371/journal.pone.0016727

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