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Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel

BACKGROUND: ARHI is a Ras-related imprinted gene that inhibits cancer cell growth and motility. ARHI is downregulated in the majority of breast cancers, and loss of its expression is associated with its progression from ductal carcinoma in situ (DCIS) to invasive disease. In ovarian cancer, re-expre...

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Detalles Bibliográficos
Autores principales: Zou, Chun-Fang, Jia, Luoqi, Jin, Hongyan, Yao, Ming, Zhao, Naiqing, Huan, Jin, Lu, Zhen, Bast, Robert C, Feng, Youji, Yu, Yinhua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032751/
https://www.ncbi.nlm.nih.gov/pubmed/21244707
http://dx.doi.org/10.1186/1471-2407-11-22