Rho GTPase Cdc42 Is a Direct Interacting Partner of Adenomatous Polyposis Coli Protein and Can Alter Its Cellular Localization

Adenomatous Polyposis Coli (APC) is a tumor suppressor gene product involved in colon cancer. APC is a large multidomain molecule of 2843 amino acid residues and connects cell-cell adhesion, the F-actin/microtubule cytoskeleton and the nucleus. Here we show that Cdc42 interacts directly with the fir...

Descripción completa

Detalles Bibliográficos
Autores principales: Sudhaharan, Thankiah, Goh, Wah Ing, Sem, Kai Ping, Lim, Kim Buay, Bu, Wenyu, Ahmed, Sohail
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032772/
https://www.ncbi.nlm.nih.gov/pubmed/21311754
http://dx.doi.org/10.1371/journal.pone.0016603

Ejemplares similares

Ejemplares similares