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Diversity in Viral Anti-PKR Mechanisms: A Remarkable Case of Evolutionary Convergence

Most viruses express during infection products that prevent or neutralize the effect of the host dsRNA activated protein kinase (PKR). Translation of Sindbis virus (SINV) mRNA escapes to PKR activation and eIF2 phosphorylation in infected cells by a mechanism that requires a stem loop structure in v...

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Detalles Bibliográficos
Autores principales:	Domingo-Gil, Elena, Toribio, René, Nájera, José Luis, Esteban, Mariano, Ventoso, Iván
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032782/ https://www.ncbi.nlm.nih.gov/pubmed/21311764 http://dx.doi.org/10.1371/journal.pone.0016711

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