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Different Binding Properties and Function of CXXC Zinc Finger Domains in Dnmt1 and Tet1

Several mammalian proteins involved in chromatin and DNA modification contain CXXC zinc finger domains. We compared the structure and function of the CXXC domains in the DNA methyltransferase Dnmt1 and the methylcytosine dioxygenase Tet1. Sequence alignment showed that both CXXC domains have a very...

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Detalles Bibliográficos
Autores principales:	Frauer, Carina, Rottach, Andrea, Meilinger, Daniela, Bultmann, Sebastian, Fellinger, Karin, Hasenöder, Stefan, Wang, Mengxi, Qin, Weihua, Söding, Johannes, Spada, Fabio, Leonhardt, Heinrich
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032784/ https://www.ncbi.nlm.nih.gov/pubmed/21311766 http://dx.doi.org/10.1371/journal.pone.0016627

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