Cathepsin-D, a Key Protease in Breast Cancer, Is Up-Regulated in Obese Mouse and Human Adipose Tissue, and Controls Adipogenesis

The aspartic protease cathepsin-D (cath-D) is overexpressed by human epithelial breast cancer cells and is closely correlated with poor prognosis in breast cancer. The adipocyte is one of the most prominent cell types in the tumor-microenvironment of breast cancer, and clinical studies have shown th...

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Detalles Bibliográficos
Autores principales: Masson, Olivier, Prébois, Christine, Derocq, Danielle, Meulle, Aline, Dray, Cédric, Daviaud, Danielle, Quilliot, Didier, Valet, Philippe, Muller, Catherine, Liaudet-Coopman, Emmanuelle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032791/
https://www.ncbi.nlm.nih.gov/pubmed/21311773
http://dx.doi.org/10.1371/journal.pone.0016452

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