Cargando…

Analysis of Microtubule Dynamic Instability Using a Plus End Growth Marker

Regulation of microtubule dynamics is essential for many cell biological processes, and is likely to be variable between different subcellular regions. We describe a computational approach to analyze microtubule dynamics by detecting growing microtubule plus ends. Our algorithm tracks all EB1-EGFP c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matov, Alexandre, Applegate, Kathryn, Kumar, Praveen, Thoma, Claudio, Krek, Wilhelm, Danuser, Gaudenz, Wittmann, Torsten
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032800/ https://www.ncbi.nlm.nih.gov/pubmed/20729842 http://dx.doi.org/10.1038/nmeth.1493

Ejemplares similares

Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability
por: Thoma, Claudio R., et al.
Publicado: (2010)

GSK3β phosphorylation modulates CLASP–microtubule association and lamella microtubule attachment
por: Kumar, Praveen, et al.
Publicado: (2009)

Automated Screening of Microtubule Growth Dynamics Identifies MARK2 as a Regulator of Leading Edge Microtubules Downstream of Rac1 in Migrating Cells
por: Nishimura, Yukako, et al.
Publicado: (2012)

Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis
por: Myers, Kenneth A., et al.
Publicado: (2011)

Directly probing the mechanical properties of the spindle and its matrix
por: Gatlin, Jesse C., et al.
Publicado: (2010)

Microtubule-dependent transport and dynamics of vimentin intermediate filaments
por: Hookway, Caroline, et al.
Publicado: (2015)

EBs clip CLIPs to growing microtubule ends
por: Wittmann, Torsten
Publicado: (2008)

Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindle
por: Yang, Ge, et al.
Publicado: (2008)

A Metastable Intermediate State of Microtubule Dynamic Instability That Differs Significantly between Plus and Minus Ends
por: Tran, P.T., et al.
Publicado: (1997)

Kinesin-14 motors participate in a force balance at microtubule plus-ends to regulate dynamic instability
por: Ogren, Allison, et al.
Publicado: (2022)

Microtubule plus tips: A dynamic route to chromosomal instability
por: Stolz, Ailine, et al.
Publicado: (2014)

γ-Tubulin ring complexes regulate microtubule plus end dynamics
por: Bouissou, Anaïs, et al.
Publicado: (2009)

Dynamic Localization of CLIP-170 to Microtubule Plus Ends Is Coupled to Microtubule Assembly
por: Diamantopoulos, Georgios S., et al.
Publicado: (1999)

Remote control of microtubule plus-end dynamics and function from the minus-end
por: Chen, Xiuzhen, et al.
Publicado: (2019)

DDA3 associates with microtubule plus ends and orchestrates microtubule dynamics and directional cell migration
por: Zhang, Liangyu, et al.
Publicado: (2013)

Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker
por: Adikes, Rebecca C., et al.
Publicado: (2018)

A conceptual view at microtubule plus end dynamics in neuronal axons
por: Voelzmann, André, et al.
Publicado: (2016)

Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth
por: Lowery, Laura Anne, et al.
Publicado: (2013)

The plus ends of stable microtubules are the exclusive nucleating structures for microtubules in the axon
Publicado: (1992)

Microtubule dynamics regulation contributes to endothelial morphogenesis
por: Lyle, Karen S., et al.
Publicado: (2012)

TACC3 is a microtubule plus end–tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types
por: Nwagbara, Belinda U., et al.
Publicado: (2014)

Microtubule plus-end dynamics link wound repair to the innate immune response
por: Taffoni, Clara, et al.
Publicado: (2020)

Interface-acting nucleotide controls polymerization dynamics at microtubule plus- and minus-ends
por: McCormick, Lauren A, et al.
Publicado: (2023)

Targeting and transport: How microtubules control focal adhesion dynamics
por: Stehbens, Samantha, et al.
Publicado: (2012)

Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth
por: David, Ana F., et al.
Publicado: (2019)

The microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics
por: Currie, Joshua D., et al.
Publicado: (2011)

Dynamic instability of microtubules is regulated by force
por: Janson, Marcel E., et al.
Publicado: (2003)

The role of dynamic instability in microtubule organization
por: Horio, Tetsuya, et al.
Publicado: (2014)

Novel Arabidopsis microtubule-associated proteins track growing microtubule plus ends
por: Wong, Jeh Haur, et al.
Publicado: (2017)

GTP-tubulin loves microtubule plus ends but marries the minus ends
por: Wordeman, Linda
Publicado: (2019)

TIP maker and TIP marker; EB1 as a master controller of microtubule plus ends
por: Vaughan, Kevin T.
Publicado: (2005)

Microtubule plus-end tracking proteins in neuronal development
por: van de Willige, Dieudonnée, et al.
Publicado: (2016)

Reconstitution of dynein transport to the microtubule plus end by kinesin
por: Roberts, Anthony J, et al.
Publicado: (2014)

Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia
por: Bowen, Jonathan R., et al.
Publicado: (2011)

TACC3 Regulates Microtubule Plus-End Dynamics and Cargo Transport in Interphase Cells
por: Furey, Colleen, et al.
Publicado: (2020)

Dynamic Regulation Genes at Microtubule Plus Ends: A Novel Class of Glioma Biomarkers
por: Wang, Wenwen, et al.
Publicado: (2023)

Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
por: Green, Rebecca A., et al.
Publicado: (2003)

Xenopus TACC1 is a microtubule plus‐end tracking protein that can regulate microtubule dynamics during embryonic development
por: Lucaj, Christopher M., et al.
Publicado: (2015)

Generation of microtubule stability subclasses by microtubule- associated proteins: implications for the microtubule "dynamic instability" model
Publicado: (1985)

Dynamic behavior of GFP–CLIP-170 reveals fast protein turnover on microtubule plus ends
por: Dragestein, Katharina A., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_hlfup7m9ft9ng26k7q8vkhli45