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Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide

Topoisomerase II inhibitors are effective chemotherapeutic agents in the treatment of cancer, in spite of being associated with the development of secondary leukemia. Our purpose was to determine the effects of etoposide on different genomic regions, aiming at discovering whether there are preferent...

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Detalles Bibliográficos
Autores principales:	Brassesco, María Sol, Montaldi, Ana Paula, Sakamoto-Hojo, Elza Tiemi
Formato:	Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2009
Materias:	Mutagenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032972/ https://www.ncbi.nlm.nih.gov/pubmed/21637660 http://dx.doi.org/10.1590/S1415-47572009000100022

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