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Non-random pre-transcriptional evolution in HIV-1. A refutation of the foundational conditions for neutral evolution
The complete base sequence of HIV-1 virus and GP120 ENV gene were analyzed to establish their distance to the expected neutral random sequence. An especial methodology was devised to achieve this aim. Analyses included: a) proportion of dinucleotides (signatures); b) homogeneity in the distribution...
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| Formato: | Texto |
| Lenguaje: | English |
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Sociedade Brasileira de Genética
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032973/ https://www.ncbi.nlm.nih.gov/pubmed/21637663 http://dx.doi.org/10.1590/S1415-47572009005000025 |