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Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans
We present an optogenetic illumination system capable of real-time light delivery with high spatial resolution to specified targets in freely moving Caenorhabditis elegans. A tracking microscope records the motion of an unrestrained worm expressing Channelrhodopsin-2 or Halorhodopsin/NpHR in specifi...
Autores principales: | Leifer, Andrew M, Fang-Yen, Christopher, Gershow, Marc, Alkema, Mark J, Samuel, Aravinthan D T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032981/ https://www.ncbi.nlm.nih.gov/pubmed/21240279 http://dx.doi.org/10.1038/nmeth.1554 |
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