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Iron Metabolism in Thalassemia and Sickle Cell Disease.
There are two main mechanisms by which iron overload develops in thalassemias: increased iron absorption due to ineffective erythropoiesis and blood transfusions. In nontransfused patients with severe thalassemia, abnormal dietary iron absorption increases body iron burden between 2 and 5 g per year...
Autores principales: | Mariani, Raffaella, Trombini, Paola, Pozzi, Matteo, Piperno, Alberto |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Università Cattolica del Sacro Cuore
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033158/ https://www.ncbi.nlm.nih.gov/pubmed/21415988 http://dx.doi.org/10.4084/MJHID.2009.006 |
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