The MCL-1 BH3 Helix is an Exclusive MCL-1 inhibitor and Apoptosis Sensitizer

The development of selective inhibitors for discrete anti-apoptotic BCL-2 family proteins implicated in pathologic cell survival remains a formidable but pressing challenge. Precisely tailored compounds would serve as molecular probes and targeted therapies to study and treat human diseases driven b...

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Detalles Bibliográficos
Autores principales: Stewart, Michelle L., Fire, Emiko, Keating, Amy E., Walensky, Loren D.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033224/
https://www.ncbi.nlm.nih.gov/pubmed/20562877
http://dx.doi.org/10.1038/nchembio.391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033224/
https://www.ncbi.nlm.nih.gov/pubmed/20562877
http://dx.doi.org/10.1038/nchembio.391

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