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A role for pancreatic beta-cell secretory hyperresponsiveness in catch-up growth hyperinsulinemia: Relevance to thrifty catch-up fat phenotype and risks for type 2 diabetes

Current notions about mechanisms by which catch-up growth predisposes to later type 2 diabetes center upon those that link hyperinsulinemia with an accelerated rate of fat deposition (catch-up fat). Using a rat model of semistarvation-refeeding in which catch-up fat is driven solely by elevated meta...

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Detalles Bibliográficos
Autores principales: Casimir, Marina, de Andrade, Paula B, Gjinovci, Asllan, Montani, Jean-Pierre, Maechler, Pierre, Dulloo, Abdul G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033236/
https://www.ncbi.nlm.nih.gov/pubmed/21244699
http://dx.doi.org/10.1186/1743-7075-8-2