Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats

BACKGROUND: Oxaliplatin is a platinum-based chemotherapy drug characterized by the development of acute and chronic peripheral neuropathies. The chronic neuropathy is a dose-limiting toxicity. We previously reported that repeated administration of oxaliplatin induced cold hyperalgesia in the early p...

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Detalles Bibliográficos
Autores principales: Mihara, Yuki, Egashira, Nobuaki, Sada, Hikaru, Kawashiri, Takehiro, Ushio, Soichiro, Yano, Takahisa, Ikesue, Hiroaki, Oishi, Ryozo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033350/
https://www.ncbi.nlm.nih.gov/pubmed/21247499
http://dx.doi.org/10.1186/1744-8069-7-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033350/
https://www.ncbi.nlm.nih.gov/pubmed/21247499
http://dx.doi.org/10.1186/1744-8069-7-8

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