Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment

BACKGROUND: Methotrexate (MTX) is the most commonly prescribed disease-modifying antirheumatic drug (DMARD) in rheumatoid arthritis. ATP-binding cassette transporter-A1 (ABCA1) and 27-Hydroxylase (HY27) are known antiatherogenic proteins that promote cellular cholesterol efflux. In THP-1 macrophages...

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Detalles Bibliográficos
Autores principales: Chen, Der-Yuan, Chih, Hui-Min, Lan, Joung-Liang, Chang, Hsin-Yueh, Chen, Wei-Wen, Chiang, En-Pei Isabel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033360/
https://www.ncbi.nlm.nih.gov/pubmed/21232092
http://dx.doi.org/10.1186/1741-7015-9-4

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