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Pharmacodynamic Modeling of Anti-Cancer Activity of Tetraiodothyroacetic Acid in a Perfused Cell Culture System

Unmodified or as a poly[lactide-co-glycolide] nanoparticle, tetraiodothyroacetic acid (tetrac) acts at the integrin αvβ3 receptor on human cancer cells to inhibit tumor cell proliferation and xenograft growth. To study in vitro the pharmacodynamics of tetrac formulations in the absence of and in con...

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Detalles Bibliográficos
Autores principales:	Lin, Hung-Yun, Landersdorfer, Cornelia B., London, David, Meng, Ran, Lim, Chang-Uk, Lin, Cassie, Lin, Sharon, Tang, Heng-Yuan, Brown, David, Van Scoy, Brian, Kulawy, Robert, Queimado, Lurdes, Drusano, George L., Louie, Arnold, Davis, Faith B., Mousa, Shaker A., Davis, Paul J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033367/ https://www.ncbi.nlm.nih.gov/pubmed/21304935 http://dx.doi.org/10.1371/journal.pcbi.1001073

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