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Accurate Quantification of Functional Analogy among Close Homologs

Correctly evaluating functional similarities among homologous proteins is necessary for accurate transfer of experimental knowledge from one organism to another, and is of particular importance for the development of animal models of human disease. While the fact that sequence similarity implies fun...

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Detalles Bibliográficos
Autores principales: Chikina, Maria D., Troyanskaya, Olga G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033368/
https://www.ncbi.nlm.nih.gov/pubmed/21304936
http://dx.doi.org/10.1371/journal.pcbi.1001074

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